Monday, nicknamed the Greatest Day Of Tennis, began with Li Na avenging a 2009 loss here to Aga Radwanska.
Also among the early winners was Vera Zvonareva, who advanced when Jelena Jankovic stopped with a back injury.
Marion Bartoli was looking strong in the early goings against Tsvetana Pironkova, leading by a break.
Marion Bartoli had been to the final at the All-England Club before, but it wasn't to be this time.
Having never been beyond the second round of a major, Tsvetana Pironkova reached her first Slam quarterfinal.
Venus Williams was down a break twice in the second set but rallied to win a tight one against Jarmila Groth.
Glistening in the summer weather, strawberries - and cream, of course - were a hot ticket item on Monday.
Kim Clijsters was blown out in the first set but reached the quarters with a 26 62 63 win over Justine Henin.
Justine Henin contemplated her missed opportunities after falling to 0-3 this year against Kim Clijsters.
Petra Kvitova routed No.3 seed Caroline Wozniacki in the shortest match of the tournament, 62 60.
Caroline Wozniacki had done a round better every year here but settled for a second straight round of 16 finish.
Kaia Kanepi became the first qualifier in four years to reach the quarters here with a win over Klara Zakopalova.
Serena Williams' game - and nails - were in full flight as she took on Maria Sharapova in the fourth round.
Maria Sharapova was on target, giving herself three set points in the first set against Serena Williams...
Serena Williams saved them all and went on to beat Maria Sharapova for the fifth straight time, 76(9) 64.