Kveta Peschke and Kata Srebotnik had beaten Liezel Huber and Lisa Raymond in their only previous meeting.
But Liezel Huber and Lisa Raymond were too tough on the day, recording a 64 64 win to take the title.
Only two players have won year-end doubles with three different partners - Lisa Raymond, Lindsay Davenport.
Petra Kvitova did some explosiveness exercises before taking the court for her final with Vika Azarenka.
Petra Kvitova was interviewed by Katrina Adams. Kvitova had won her last three meetings with Vika Azarenka.
Over 13,000 fans packed Sinan Erdem Dome to watch the TEB BNP Paribas WTA Championships singles final.
She lost the first five games, but Victoria Azarenka managed to take the singles final to a deciding set.
Petra Kvitova closed Victoria Azarenka out in an electric final, 75 46 63, then dropped to the ground.
Petra Kvitova ran straight for her team after winning the sixth and second-biggest title of a dream season.
Ayda Uluc, President of the Turkish Tennis Federation, exchanged gifts with WTA CEO Stacey Allaster.
Doubles stars Liezel Huber, Lisa Raymond, Katarina Srebotnik and Kveta Peschke with their finals trophies.
Victoria Azarenka and Petra Kvitova with their singles trophies. Kvitova is now 4-2 against Azarenka.
Petra Kvitova rose to No.2 in the world by winning the year-end TEB BNP Paribas WTA Championships title.
Kveta Peschke and Katarina Srebotnik received special trophies for finishing 2011 as the No.1 doubles team.
Petra Kvitova is the third player to win the year-ender on debut, after Serena Williams and Maria Sharapova.