Australian No.2 Jarmila Gajdosova was one half of a popular pairing with Bethanie Mattek-Sands.
Teen stars Laura Robson and Ashleigh Barty were a wildcard pair in the draw but fell first round.
Zheng Jie and Polona Hercog made the third round together. Zheng won the title in 2006 with Yan Zi.
The Rodionova sisters won a round before falling to eventual finalists Sara Errani and Roberta Vinci.
No.5 seeds Maria Kirilenko and Nadia Petrova had to retire in the 16s due to an injured Kirilenko.
Gisela Dulko and Flavia Pennetta had won the Australian Open in 2011 and were the No.4 seeds in 2012.
In mixed doubles, Japanese pairing Kimiko Date-Krumm and Kei Nishikori were drawing packed crowds.
They weren't the only popular all-country mixed pair - India's Sania Mirza and Mahesh Bhupathi, too.
Svetlana Kuznetsova and Vera Zvonareva upset Gisela Dulko and Flavia Pennetta in the third round.
No.11 seeds Sara Errani and Roberta Vinci took out two Top 8 seeds en route to their first Slam final.
Svetlana Kuznetsova and Vera Zvonareva were the first all-Russian duo to win a major doubles title.
Bethanie Mattek-Sands reached her first Grand Slam final of any kind in the mixed doubles tournament.
Bethanie Mattek-Sands and talented Romanian Horia Tecau were the No.8-seeded pair in the mixed draw.
Bethanie Mattek-Sands and Horia Tecau beat Elena Vesnina and Leander Paes in the final, 63 57 103.
The mixed doubles final was part of an epic final day, with the men's final next on Rod Laver Arena.