Ana Ivanovic was one of the first winners of the day, beating Maria Jose Martinez Sanchez, 63 36 63.
Olga Govortsova followed Ana Ivanovic into the next round with an identical 63 36 63 win over Annika Beck.
Kuala Lumpur champion Hsieh Su-Wei beat Stephanie Foretz Gacon in one of the first second rounds, 64 61.
Crowd favorite Maria Kirilenko also scored a second round win, beating Lourdes Dominguez Lino, 61 62.
World No.5 Sam Stosur became one of the first big casualties of the fortnight, falling to Arantxa Rus.
Arantxa Rus' 62 06 64 win was her second Top 5 win, having beaten Kim Clijsters at the 2011 French Open.
World No.7 Caroline Wozniacki was also on the losing end of a marathon, hers a first round match-up.
Three matches, three Top 10 opponents, three Top 10 wins - Tamira Paszek just keeps lifting her game.
Andrea Hlavackova fell to former No.1 Kim Clijsters under the retractable roof of Centre Court, 63 63.
Li Na, the 2011 French Open champion, was bounced on one of the outside courts by Sorana Cirstea, 63 64.
Maria Sharapova removed her jacket and got ready to take on dangerous grass courter Tsvetana Pironkova.
After saving a slew of set points and leading 76(3) 31, the World No.1's match was suspended due to darkness.