With that in mind, here are 10 Things To Know about the Wimbledon final - it's going to be a doozy!
1) Serena is a win away from her second Serena Slam.
Serena's first Serena Slam comprised of the 2002 French Open, 2002 Wimbledon, 2002 US Open and 2003 Australian Open, and with the 2014 US Open, 2015 Australian Open and 2015 French Open already under her belt, she's a win away from the second Serena Slam of her illustrious career.
2) Muguruza was four years old the last time a Spanish woman won a major.
If Muguruza wins, she'll be the first Spanish woman to win a Grand Slam title since the 1998 French Open (Arantxa Sánchez-Vicario) and the first to win Wimbledon since 1994 (Conchita Martínez).
3) Serena is trying to become the oldest Grand Slam champion in the Open Era.
Is 33 the new 23? If Serena wins, she'll be the oldest woman to win a Grand Slam title in the Open Era at 33 years and 289 days, beating Martina Navratilova, who won 1990 Wimbledon at 33 and 263.
4) Serena is going for her 21st Grand Slam title - one shy of the Open Era record.
If Serena wins, she'll have 21 Grand Slam titles, the second-most in the Open Era, male or female (Steffi Graf won 22) and third-most in tennis history, male or female (Margaret Court won 24).
5) The No.20-seeded Muguruza won't be the most surprising champion here...
One might think the No.20 seed would be the most surprising champion here, but, surprisingly, it wouldn't be. A No.23-seeded Venus Williams won the fourth of her five Wimbledon titles here in 2007.
6) Muguruza will break the Top 10 after Wimbledon.
By virtue of reaching the final, Muguruza will become the 113th player - and fourth Spaniard - ever to break the Top 10. Who were the first three Spaniards to break the Top 10? Find out here.
7) Muguruza is just the second player born in 1992 or later to reach a Grand Slam final.
Is the new generation here? The 1993-born Muguruza is only the second player born in 1992 or later to reach a Grand Slam final, after 1994-born Eugenie Bouchard (who made the 2014 Wimbledon final).
8) Serena is an incredible 20-4 in Grand Slam finals.
Serena has only lost four Grand Slam finals: the 2001 US Open (to Venus Williams), 2004 Wimbledon (to Maria Sharapova), 2008 Wimbledon (to Venus Williams) and 2011 US Open (to Sam Stosur).
9) The Road To Singapore is really starting to take shape...
Serena, who will stretch her lead atop the Road To Singapore leaderboard regardless of what happens today, already qualified for the BNP Paribas WTA Finals Singapore presented by SC Global on Monday. By virtue of reaching the final, Muguruza will rise from No.17 into the Top 8.
10) And perhaps, most importantly, the head-to-head has been tight.
Their first meeting, where Serena beat Muguruza at the 2013 Australian Open, 6-2, 6-0, might be a little irrelevant at the moment - Muguruza wasn't even in the Top 100 at the time (she was No.112).
But the Spaniard has given Serena all kinds of trouble in their last two meetings. She beat her in the second round of the 2014 French Open, 6-2, 6-2, the worst Grand Slam loss of her career, and she pushed her to a 2-6, 6-3, 6-2 scoreline in the fourth round of the Australian Open earlier this year.